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Volume-II

, Issue-I

(FALL 2017)

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01 - Nanoformulated Myristic Acid for Antimicrobial Applications

http://dx.doi.org/10.31703/gpsr.2017(II-I).01
10.31703/gpsr.2017(II-I).01      Published : Dec 2017

Abstract

    Free fatty acids possess antimicrobial properties in the natural defense system of many eukaryotes. In this study, we synthesized nanoformulations of myristic acid for antimicrobial activity. The myristic acid nanoformulations (MN) were unstable due to crystallization. This problem was overcome by the addition of the liquid fatty acids and by using two surfactants of hydrophilic and lipophilic nat... Details

    Antimicrobial Resistance, MRSA, Fatty Acids, Algae, Nanoparticles, Antibiotics

    (1) Mubashar Rehmana
    Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Adeel Arshad
    Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Punjab, Pakistan.
    (3) Muhammad Asadullah Madni
    Professor, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Punjab, Pakistan.
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02 - Formulation and In Vitro Evaluation of Sustained Release Matrix Tablets of Venl

http://dx.doi.org/10.31703/gpsr.2017(II-I).02
10.31703/gpsr.2017(II-I).02      Published : Dec 2017

Abstract

    Sustained release matrix tablets of venlafaxine were formulated using synthetic polymers (ethylcellulose & hydroxypropyl methylcellulose). Six (06) different batches of matrix tablets of venlafaxine (dose 75 mg) were prepared by the wet granulation method. Polymers were used alone or in combination. The physical properties of compressed tablets were evaluated. In vitro release drug studies wer... Details

    Sustained Release Matrix Tablets, Venlafaxine, Ethyl Cellulose (EC), hydroxypropyl methylcellulose

    (1) Zubair Anwar
    M.Phil Scholar, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Lahore, Punjab, Pakistan.
    (2) Tanveer Ahmed Khan
    PhD Scholar, Saulat Institute of Pharmaceutical Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (3) Muhammad Farhan Sohail
    Associate Professor, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Lahore, Punjab, Pakistan.
    (4) Maryam Anwar
    PhD Scholar, Saulat Institute of Pharmaceutical Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
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03 - A Deeper Insight into Pharmacokinetics of Drugs Following one Compartment Model

http://dx.doi.org/10.31703/gpsr.2017(II-I).03
10.31703/gpsr.2017(II-I).03      Published : Dec 2017

Abstract

    This article discusses the mathematical pharmacokinetic models with reference to one open compartment model in detail. Four types of models, IV, bolus, extravascular 1st and 0 order, have been studied. Mathematical approaches to predict the pharmacokinetic parameters, including elimination half-life, rate constant and drug clearance, have been included. This article focuses on the significance of ... Details

    One Compartment Model, Open Model, Pharmacokinetic Models, Elimination Half-Life, Drug Clearance, Elimination Rate Constant, Pharmacokinetics (PK).

    (1) Syeda Komal Fatima
    Undergraduate Student, Department of Pharmaceutics, Faculty of Pharmacy, Islamia University Bahawalpur, Bahawalpur, Punjab, Pakistan.
    (2) Ayesha Sabir
    Undergraduate Student, Department of Pharmaceutics, Faculty of Pharmacy, Islamia University Bahawalpur, Bahawalpur, Punjab, Pakistan.
    (3) Fahad Pervai
    Associate Professor, Department of Pharmaceutics, Faculty of Pharmacy, Islamia University Bahawalpur, Bahawalpur, Punjab, Pakistan.
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04 - Evaluation of Prevalence of Complications of Measles

http://dx.doi.org/10.31703/gpsr.2017(II-I).04
10.31703/gpsr.2017(II-I).04      Published : Dec 2017

Abstract

    Study and evaluation of the prevalence of measles and its complication in vaccinated and non- vaccinated patients. To evaluate the prevalence of complications of measles among different age groups of children in the pedriatric ward. Clinical description of a case series. Children of different age groups suffering from measles. We have observed 315 measles patients in the pediatric ward of Bahawal ... Details

    Measles, Vaccine, Patients

    (1) Hina Shoukat
    Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Punjab, Pakistan.
    (2) Fahad Pervaiz
    Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Punjab, Pakistan.
    (3) Sobia Noreen
    Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Punjab, Pakistan.
    (4) Ayesha Khadim
    Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Punjab, Pakistan.
    (5) Maira Latif
    Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Punjab, Pakistan.
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05 - Determination of Pharmacokinetic Parameters by the Application of Noncompartment

http://dx.doi.org/10.31703/gpsr.2017(II-I).05
10.31703/gpsr.2017(II-I).05      Published : Dec 2017

Abstract

    Pharmacokinetic models utilize mathematical terms to do pharmacokinetic analysis. Pharmacokinetic analysis of drug is defined as an experimental method to find drug exposure once administered or how does drug behave inside the body. Pharmacokinetic parameters determined include drug absorption, distribution, metabolism and elimination after its administration. These two types of models are used co... Details

    Compartment, Non -compartment Model, AUC, AUMC, MRT, Drug

    (1) Sidra Altaf
    Undergrad Student (9th semester), Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
    (2) Asma Kaleem
    Undergrad Student (9th semester), Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
    (3) Syeda Komal Fatima
    Undergrad Student (9th semester), Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
    (4) Ayesha Sabir
    Undergrad Student (9th semester), Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
    (5) Imran Khan
    Associate Professor, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Lahore, Pakistan.
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