01 - Nanoformulated Myristic Acid for Antimicrobial Applications
http://dx.doi.org/10.31703/gpsr.2017(II-I).0110.31703/gpsr.2017(II-I).01 Published : Dec 2017
-
Free fatty acids possess antimicrobial properties in the natural defense system of many eukaryotes. In this study, we synthesized nanoformulations of myristic acid for antimicrobial activity. The myristic acid nanoformulations (MN) were unstable due to crystallization. This problem was overcome by the addition of the liquid fatty acids and by using two surfactants of hydrophilic and lipophilic nat... Details
-
Antimicrobial Resistance, MRSA, Fatty Acids, Algae, Nanoparticles, Antibiotics
-
(1) Mubashar Rehmana
Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
(2) Adeel Arshad
Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Punjab, Pakistan.
(3) Muhammad Asadullah Madni
Professor, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Punjab, Pakistan.
02 - Formulation and In Vitro Evaluation of Sustained Release Matrix Tablets of Venl
http://dx.doi.org/10.31703/gpsr.2017(II-I).0210.31703/gpsr.2017(II-I).02 Published : Dec 2017
-
Sustained release matrix tablets of venlafaxine were formulated using synthetic polymers (ethylcellulose & hydroxypropyl methylcellulose). Six (06) different batches of matrix tablets of venlafaxine (dose 75 mg) were prepared by the wet granulation method. Polymers were used alone or in combination. The physical properties of compressed tablets were evaluated. In vitro release drug studies wer... Details
-
Sustained Release Matrix Tablets, Venlafaxine, Ethyl Cellulose (EC), hydroxypropyl methylcellulose
-
(1) Zubair Anwar
M.Phil Scholar, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Lahore, Punjab, Pakistan.
(2) Tanveer Ahmed Khan
PhD Scholar, Saulat Institute of Pharmaceutical Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
(3) Muhammad Farhan Sohail
Associate Professor, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Lahore, Punjab, Pakistan.
03 - A Deeper Insight into Pharmacokinetics of Drugs Following one Compartment Model
http://dx.doi.org/10.31703/gpsr.2017(II-I).0310.31703/gpsr.2017(II-I).03 Published : Dec 2017
-
This article discusses the mathematical pharmacokinetic models with reference to one open compartment model in detail. Four types of models, IV, bolus, extravascular 1st and 0 order, have been studied. Mathematical approaches to predict the pharmacokinetic parameters, including elimination half-life, rate constant and drug clearance, have been included. This article focuses on the significance of ... Details
-
One Compartment Model, Open Model, Pharmacokinetic Models, Elimination Half-Life, Drug Clearance, Elimination Rate Constant, Pharmacokinetics (PK).
-
(1) Syeda Komal Fatima
Undergraduate Student, Department of Pharmaceutics, Faculty of Pharmacy, Islamia University Bahawalpur, Bahawalpur, Punjab, Pakistan.
(2) Ayesha Sabir
Undergraduate Student, Department of Pharmaceutics, Faculty of Pharmacy, Islamia University Bahawalpur, Bahawalpur, Punjab, Pakistan.
(3) Fahad Pervai
Associate Professor, Department of Pharmaceutics, Faculty of Pharmacy, Islamia University Bahawalpur, Bahawalpur, Punjab, Pakistan.
04 - Evaluation of Prevalence of Complications of Measles
http://dx.doi.org/10.31703/gpsr.2017(II-I).0410.31703/gpsr.2017(II-I).04 Published : Dec 2017
-
Study and evaluation of the prevalence of measles and its complication in vaccinated and non- vaccinated patients. To evaluate the prevalence of complications of measles among different age groups of children in the pedriatric ward. Clinical description of a case series. Children of different age groups suffering from measles. We have observed 315 measles patients in the pediatric ward of Bahawal ... Details
-
Measles, Vaccine, Patients
-
(1) Hina Shoukat
Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Punjab, Pakistan.
(2) Fahad Pervaiz
Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Punjab, Pakistan.
(3) Sobia Noreen
Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Punjab, Pakistan.
05 - Determination of Pharmacokinetic Parameters by the Application of Noncompartment
http://dx.doi.org/10.31703/gpsr.2017(II-I).0510.31703/gpsr.2017(II-I).05 Published : Dec 2017
-
Pharmacokinetic models utilize mathematical terms to do pharmacokinetic analysis. Pharmacokinetic analysis of drug is defined as an experimental method to find drug exposure once administered or how does drug behave inside the body. Pharmacokinetic parameters determined include drug absorption, distribution, metabolism and elimination after its administration. These two types of models are used co... Details
-
Compartment, Non -compartment Model, AUC, AUMC, MRT, Drug
-
(1) Sidra Altaf
Undergrad Student (9th semester), Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
(2) Asma Kaleem
Undergrad Student (9th semester), Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
(3) Syeda Komal Fatima
Undergrad Student (9th semester), Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.