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FREQUENCY OF HYPERCHOLESTEREMIA IN PATIENTS PRESENTING WITH ACUTE CORONARY SYNDROME

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11 Pages : 71-77

http://dx.doi.org/10.31703/gpsr.2023(VIII-I).11      10.31703/gpsr.2023(VIII-I).11      Published : Mar 2023

Frequency Of Hypercholesteremia In Patients Presenting With Acute Coronary Syndrome

Abstract

    To assess the frequency of hypercholesteremia in patients presenting with acute coronary syndrome. From February 1, 2020, to February 1, 2021, 100 patients who presented with acute coronary syndrome underwent a retrospective study at the cardiology department of the Hayatabad Medical Complex in Peshawar. The diagnosis, lab tests, patient outcomes, and demographic information were gathered and examined. All the data analysis was done by SPSS. According to the findings, 24.0% (or 100/100) of the patients had hypercholesterolemia. The patients with hypercholesterolemia were 58.75 + 9.39 years old on average. Patients with hypercholesterolemia had a 16.6% death rate. Patients with hypercholesterolemia had a substantially increased morbidity rate (OR = 2.937, p=0.01). In the examined population, hypercholesterolemia is a significant comorbidity linked to acute coronary syndrome, and it should be appropriately managed and treated to improve the management of acute coronary syndrome.

    Hypercholeseteremia, Acute Coronary Syndrome, Morbidity, Mortality

    (1) Cheragh Hussain
    Associate Professor, Department of Cardiology, Hayatabad Medical Complex, Peshawar, KP, Pakistan.
    (2) Muhammad Asghar Khan
    Associate Professor, Department of Cardiology, Hayatabad Medical Complex, Peshawar, KP, Pakistan.
    (3) Yasir hayat
    Assistant Professor, Department of Cardiology, Hayatabad Medical Complex, Peshawar, KP, Pakistan.
    (4) Nasir
    Assistant Professor, Department of Cardiology, Hayatabad Medical Complex, Peshawar, KP, Pakistan.
    (5) Mahmood ul Hassan
    Professor, Department of Cardiology, Hayatabad Medical Complex, Peshawar, KP, Pakistan
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References

  • Abdallah, M., Karrowni, W., Shamseddeen, W., Itani, S., Kobeissi, L., Ghazzal, Z., . . . Dakik, H. A. (2010). Acute coronary syndromes: clinical characteristics, management, and outcomes at the American University of Beirut Medical Center, 2002–2005. Clinical Cardiology, 33(1), E6-E13.
  • Suwaidi, J. A. (2004). Mortality caused by acute myocardial infarction in Qatari women. Heart, 90(6), 693–694. https://doi.org/10.1136/hrt.2003.014746
  • Alberti, K. G. M. M., Eckel, R. H., Grundy, S. M., Zimmet, P., Cleeman, J. I., Donato, K. A., Fruchart, J., James, W. P. T., Loria, C. M., & Smith, S. C. (2009). Harmonizing the Metabolic Syndrome. Circulation, 120(16), 1640–1645. https://doi.org/10.1161/circulationaha.109.192644
  • Austin, M. A., Hutter, C. M., Zimmern, R., & Humphries, S. E. (2004). Familial Hypercholesterolemia and Coronary Heart Disease: A HuGE Association Review. American Journal of Epidemiology, 160(5), 421–429. https://doi.org/10.1093/aje/kwh237
  • El-Menyar, A., Zubaid, M., Rashed, W., Almahmeed, W., Al-Lawati, J., Sulaiman, K., Al-Motarreb, A., Amin, H., Singh, R. P., & Suwaidi, J. A. (2009). Comparison of Men and Women With Acute Coronary Syndrome in Six Middle Eastern Countries. American Journal of Cardiology, 104(8), 1018–1022. https://doi.org/10.1016/j.amjcard.2009.06.003
  • El-Menyar, A., Zubaid, M., Sulaiman, K., Singh, R. P., Thani, H. A., Akbar, M., Bulbanat, B., Al- Hamdan, R. S., AlMahmmed, W., & Suwaidi, J. A. (2010). In-hospital Major Clinical Outcomes in Patients With Chronic Renal Insufficiency Presenting With Acute Coronary Syndrome: Data From a Registry of 8176 Patients. Mayo Clinic Proceedings, 85(4), 332–340. https://doi.org/10.4065/mcp.2009.0513
  • Esteghamati, A., Abbasi, M., Nakhjavani, M., Yousefizadeh, A., Basa, A. P., & Afshar, H. (2006). Prevalence of diabetes and other cardiovascular risk factors in an Iranian population with acute coronary syndrome. Cardiovascular Diabetology, 5(1). https://doi.org/10.1186/1475-2840-5-15
  • Flegal, K. M., Carroll, M. D., Ogden, C. L., & Johnson, C. V. (2002). Prevalence and Trends in Obesity Among US Adults, 1999-2000. JAMA, 288(14), 1723. https://doi.org/10.1001/jama.288.14.1723
  • Hadi, H. a. R., Zubaid, M., Mahmeed, W. A., El- Menyar, A., Alsheikh-Ali, A. A., Singh, R., Alnabti, A., Assad, N., Sulaiman, K., Al-Mallah, M. H., Amin, H., Al-Motarreb, A., Mahmoud, H., & Suwaidi, J. A. (2009). The Prevalence and Outcome of Excess Body Weight Among Middle Eastern Patients Presenting With Acute Coronary Syndrome. Angiology, 61(5), 456– 464. https://doi.org/10.1177/0003319709355801
  • Jiang, J., Zhou, Y., Li, J., Ge, J., Feng, Y., Huo, Y., & Investigators, A. S. (2018). Uncontrolled hyperlipidemia in Chinese patients who experienced acute coronary syndrome: an observational study. Therapeutics and Clinical Risk Management, Volume 14, 2255–2264. https://doi.org/10.2147/tcrm.s178318
  • Kurtulmus, N., Bos, S., Arslan, S., Kurt, T., Tükek, T., & Ince, N. (2007). Differences in risk factors for acute coronary syndromes between men and women. Acta Cardiologica, 62(3), 247–251. https://doi.org/10.2143/ac.62.3.2020813
  • Libby, P., & Ridker, P. M. (2004). Inflammation and atherosclerosis: role of C-Reactive protein in risk assessment. The American Journal of Medicine, 116(6), 9–16. https://doi.org/10.1016/j.amjmed.2004.02.006
  • Nanchen, D., Gencer, B., Muller, O., Auer, R., Aghlmandi, S., Heg, D., Klingenberg, R., Räber, L., Carballo, D., Carballo, S., Matter, C. M., Lüscher, T. F., Windecker, S., Mach, F., & Rodondi, N. (2016). Prognosis of Patients With Familial Hypercholesterolemia After Acute Coronary Syndromes. Circulation, 134(10), 698–709. https://doi.org/10.1161/circulationaha.116.023 007
  • Sobhy, M., Etriby, A. E., Nashar, A. E., Wajih, S., Horack, M., Brudi, P., Lautsch, D., Ambegaonkar, B. M., Vyas, A., & Gitt, A. K. (2018). Prevalence of lipid abnormalities and cholesterol target value attainment in Egyptian patients presenting with an acute coronary syndrome. The Egyptian Heart Journal. https://doi.org/10.1016/j.ehj.2018.05.001
  • Steg, P. G., Goldberg, R. J., Gore, J. M., Fox, K. A., Eagle, K. A., Flather, M. D., . . . Anderson, F. A. (2002). Baseline characteristics, management practices, and in-hospital outcomes of patients hospitalized with acute coronary syndromes in the Global Registry of Acute Coronary Events GRACE). The American Journal of Cardiology, 90(4), 358-363.
  • Wan, K., Zhao, J., Huang, H., Zhang, Q., Chen, X., Zeng, Z., Zhang, L., & Chen, Y. (2015). The Association between Triglyceride/High-Density Lipoprotein Cholesterol Ratio and All-Cause Mortality in Acute Coronary Syndrome after Coronary Revascularization. PLOS ONE, 10(4), e0123521. https://doi.org/10.1371/journal.pone.0123521
  • Zubaid, M., Rashed, W., Al-Khaja, N., Almahmeed, W., Al-Lawati, J., Sulaiman, K., Al-Motarreb, A., Amin, H., Al-Suwaidi, J., & AlHabib, K. F. (2008). Clinical presentation and outcomes of acute coronary syndromes in the gulf registry of acute coronary events (Gulf RACE). PubMed, 29(2), 251–255. https://pubmed.ncbi.nlm.nih.gov/18246236
  • Zubaid, M., Rashed, W., Almahmeed, W., Al-Lawati, J., Sulaiman, K., Al-Motarreb, A., Amin, H., Suwaidi, J. A., & AlHabib, K. F. (2009). Management and outcomes of Middle Eastern patients admitted with acute coronary syndromes in the Gulf Registry of Acute Coronary Events (Gulf RACE). Acta Cardiologica, 64(4), 439–446. https://doi.org/10.2143/ac.64.4.2041607

Cite this article

APA

    APA : Hussain, C., Khan, M. A., & hayat, Y. (2023). Frequency Of Hypercholesteremia In Patients Presenting With Acute Coronary Syndrome. Global Pharmaceutical Sciences Review, VIII(I), 71-77. https://doi.org/10.31703/gpsr.2023(VIII-I).11

CHICAGO

    CHICAGO : Hussain, Cheragh, Muhammad Asghar Khan, and Yasir hayat. 2023. "Frequency Of Hypercholesteremia In Patients Presenting With Acute Coronary Syndrome." Global Pharmaceutical Sciences Review, VIII (I): 71-77 doi: 10.31703/gpsr.2023(VIII-I).11

HARVARD

    HARVARD : HUSSAIN, C., KHAN, M. A. & HAYAT, Y. 2023. Frequency Of Hypercholesteremia In Patients Presenting With Acute Coronary Syndrome. Global Pharmaceutical Sciences Review, VIII, 71-77.

MHRA

    MHRA : Hussain, Cheragh, Muhammad Asghar Khan, and Yasir hayat. 2023. "Frequency Of Hypercholesteremia In Patients Presenting With Acute Coronary Syndrome." Global Pharmaceutical Sciences Review, VIII: 71-77

MLA

    MLA : Hussain, Cheragh, Muhammad Asghar Khan, and Yasir hayat. "Frequency Of Hypercholesteremia In Patients Presenting With Acute Coronary Syndrome." Global Pharmaceutical Sciences Review, VIII.I (2023): 71-77 Print.

OXFORD

    OXFORD : Hussain, Cheragh, Khan, Muhammad Asghar, and hayat, Yasir (2023), "Frequency Of Hypercholesteremia In Patients Presenting With Acute Coronary Syndrome", Global Pharmaceutical Sciences Review, VIII (I), 71-77

TURABIAN

    TURABIAN : Hussain, Cheragh, Muhammad Asghar Khan, and Yasir hayat. "Frequency Of Hypercholesteremia In Patients Presenting With Acute Coronary Syndrome." Global Pharmaceutical Sciences Review VIII, no. I (2023): 71-77. https://doi.org/10.31703/gpsr.2023(VIII-I).11