USE OF FLUORESCENT PROBE FOR THE FAST AND QUANTITATIVE DETECTION OF CHEMICALS IN THE BLOOD

http://dx.doi.org/10.31703/gpsr.2019(IV-I).01      10.31703/gpsr.2019(IV-I).01      Published : Fall 2019
Authored by : Urooj Naseem , Ayesha Ayub , Fatima Iqbal , Farhan Sohail

01 Pages : 1-10

http://dx.doi.org/10.31703/gpsr.2019(IV-I).01      10.31703/gpsr.2019(IV-I).01      Published : Dec 2019

Use of Fluorescent Probe for the Fast and Quantitative Detection of Chemicals in the Blood

    Different methods are adopted for the quantitative detection of chemicals in the blood. One of which is discussed here, i.e., the fluorescent probes that are preferred in biological systems owing to their sensitivity, high selectivity, elevated spatiotemporal resolution, and noninvasiveness. In recent years, for the identification of various chemicals, a large number of probes have been designed. For the detection as well as identification of fluorescent probes, sulfides, different chemicals such as iron, glucose, glutathione etc., in the blood are discussed. The maximum detection limits of newly synthesized fluorescent probes for different chemical analysis are studied and comparatively analyzed. Different parameters like pH, incubation time, mixing time, the detection limit of the fluorescent probes is also explored.

    Fluorescence, Fluorescent Probe, Fluorophore, Detection Limit, Hydrogen Sulphide, Iron, Glucose, Glutathione
    (1) Urooj Naseem
    Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Ayesha Ayub
    Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (3) Fatima Iqbal
    Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (4) Farhan Sohail
    Associate Professor, Riphah Institute of Pharmaceutical Sciences, Riphah international University-Lahore Campus, Lahore Pakistan.
PDF
  • Budowle, B., Leggitt, J., Defenbaugh, D., Keys, K., & Malkiewicz, S. (2000). The Presumptive Reagent Fluorescein for Detection of Dilute Bloodstains and Subsequent STR Typing of Recovered DNA, Journal of Forensic Sciences, 45, (5)1090-1092.
  • Chandan, H. R., Schiffman, J. D., & Balakrishna, R. G. (2018). Quantum dots as fluorescent probes: Synthesis, surface chemistry, energy transfer mechanisms, and applications. Sensors and Actuators B: Chemical, 258, 1191-1214.
  • Chen, B., Li, W., Lv, C., Zhao, M., Jin, H., Jin, H., & Tang, X. (2013). A fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues. The Analyst, 138(3), 946-951.
  • Gao, B., Cui, L., Pan, Y., Xue, M., Zhu, B., Zhang, G., & Dong, C. (2017). A highly selective fluorescent probe based on Michael addition for fast detection of hydrogen sulfide. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 173, 457-461.
  • Karunya, R., Jayaprakash, K. S., Gaikwad, R., Sajeesh, P., Ramshad, K., Muraleedharan, K. M., & Sen, A. K. (2019). Rapid measurement of hydrogen sulphide in human blood plasma using a microfluidic method. Scientific Reports, 9(1).
  • Kumar, A., & Pal, D. (2016). Green Fluorescent Protein and Their Applications in Advance Research, Journal of Research in Engineering and Applied Sciences.
  • Lalchhandama, K. (2016). The making of modern biotechnology: how ethidium bromide made fame. Science Vision 16 (1), 27-36.
  • Lee, F. H., Chew, C. Y., Hwu, J. R., & Tan, K. T. (2018). A biotinylated fluorescent probe for the specific and quantitative determination of blood glucose. Journal of the Chinese Chemical Society, 66, 114-118.
  • Leung, C. W. T., Hong, Y., Hanske, J., Zhao, E., Chen, S., Pletneva, E. V., & Tang, B. Z. (2013). Superior Fluorescent Probe for Detection of Cardiolipin. Analytical Chemistry, 86(2), 1263- 1268.
  • Li, H., Yang, Y., Qi, X., Zhou, X., Ren, W. X., Deng, M., & Teichmann, A. T. (2020). Design and Applications of a Novel Fluorescent Probe for Detecting Glutathione in Biological Samples. Analytica Chimica Acta.
  • Lin, X., Lu, X., Zhou, J., Ren, H., Dong, X., Zhao, W., & Chen, Z. (2019). An instantaneous fluorescent probe for the specific detection of H2S. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.
  • Liu, C., Qi, F., Wen, F., Long, L., Liu, A., & Yang, R. (2018). Fluorescence detection of glutathione and oxidized glutathione in blood with a NIR- excitable cyanine probe. Methods and Applications in Fluorescence, 6(2), 024001.
  • Long, L., Zhou, L., Wang, L., Meng, S., Gong, A., & Zhang, C. (2014). A ratiometric fluorescent probe for iron (III) and its application for detection of iron (III) in human blood serum. Analytica Chimica Acta, 812, 145-151
  • Martynov, V. I., Pakhomov, A. A., Popova, N. V., Deyev, I. E., Petrenko, A. G. (2016). Synthetic fluorophores for visualizing biomolecules in living systems, 08, 33-46.
  • Masilamani, V., Al-Zhrani, K., Al-Salhi, M., Al-Diab, A., & Al-Ageily, M. (2004). Cancer diagnosis by autofluorescence of blood components. Journal of Luminescence, 109(3-4), 143-154.
  • Matea, C., Mocan, T., Tabaran, F., Pop, T., Mosteanu, O., Puia, C., & Mocan, L. (2017). Quantum dots in imaging, drug delivery and sensor applications. International Journal of Nanomedicine, 12, 5421-5431.
  • Mathew, T., Kundan, S., Abdulsamad, M. I., Menon, S., Dharan, B. S., & Jayakumar, K. (2014). Multiple Muscular Ventricular Septal Defects: Use of Fluorescein Dye to Identify Residual Defects. The Annals of Thoracic Surgery, 97(1), 27-28.
  • Olson, K. R. (2009). Is hydrogen sulfide a circulating
  • Peng, H., Cheng, Y., Dai, C., King, A. L., Predmore, B. L., Lefer, D. J., & Wang, B. (2011). A Fluorescent Probe for Fast and Quantitative Detection of Hydrogen Sulfide in Blood. Angewandte Chemie International Edition, 50(41), 9672-9675.
  • Qian, Y., Zhang, L., Ding, S., Deng, X., He, C., Zheng, X. E., & Zhao, J. (2012). A fluorescent probe for rapid detection of hydrogen sulfide in blood plasma and brain tissues in mice. Chemical Science, 3(10), 2920.
  • Olson, K. R. (2012). A Practical Look at the Chemistry and Biology of Hydrogen Sulfide. Antioxidants & Redox Signaling, 17(1), 32-44.
  • Sun, X., & James, T. D. (2015). Glucose Sensing in Supramolecular Chemistry. Chemical Reviews, 115(15), 8001-8037.
  • Ueno, T., Nagano, T. Fluorescent probes for sensing and imaging. Nat. Methods 2011, 8, 642−645
  • Wang, C., Wang, Y., Wang, G., Huang, C., & Jia, N. (2019) A new mitochondria-targeting fluorescent probe for ratiometric detection of H2O2 in live cells, Analytica Chimica Acta, S0003-2670(19), 31368-6
  • Whitfield, N. L., Kreimier, E. L., Verdial, F. C., Skovgaard, N., & Olson, K. R. (2008). Reappraisal of H2S/sulfide concentration in vertebrate blood and its potential significance in ischemic preconditioning and vascular signalling. American Journal of Physiology- Regulatory, Integrative and Comparative Physiology, 294(6), 1930-1937.
  • Xuan, W., Sheng, C., Cao, Y., He, W., & Wang, W. (2012). Fluorescent Probes for the Detection of Hydrogen Sulfide in Biological Systems. Angewandte Chemie International Edition, 51(10), 2282-2284.
  • Yang, G., Zhang, J., Zhu, S., Wang, Y., Feng, X., Yan, M., & Yu, J. (2018). Fast response and highly selective detection of hydrogen sulfide with a ratiometric two-photon fluorescent probe and its application for bioimaging. Sensors and Actuators B: Chemical, 261, 51-57
  • Yang, X., Wang, Y., Liu, R., Zhang, Y., Tang, J., Yang, E., & Ye, Y. (2019). A novel ICT-based two-photon and NIR fluorescent probe for labile Fe2 detection and cell imaging in living cells. Sensors and Actuators B: Chemical.
  • Zeng, Y. S., Gao, R. C., Wu, T. W., Cho, C., & Tan, K. T. (2016). Fluorescent Probe Encapsulated in SNAP-Tag Protein Cavity to Eliminate Non- specific Fluorescence and Increase Detection Sensitivity. Bioconjugate Chemistry, 27(8), 1872-1879.

Cite this article

    APA : Naseem, U., Ayub, A., & Iqbal, F. (2019). Use of Fluorescent Probe for the Fast and Quantitative Detection of Chemicals in the Blood. Global Pharmaceutical Sciences Review, IV(I), 1-10. https://doi.org/10.31703/gpsr.2019(IV-I).01
    CHICAGO : Naseem, Urooj, Ayesha Ayub, and Fatima Iqbal. 2019. "Use of Fluorescent Probe for the Fast and Quantitative Detection of Chemicals in the Blood." Global Pharmaceutical Sciences Review, IV (I): 1-10 doi: 10.31703/gpsr.2019(IV-I).01
    HARVARD : NASEEM, U., AYUB, A. & IQBAL, F. 2019. Use of Fluorescent Probe for the Fast and Quantitative Detection of Chemicals in the Blood. Global Pharmaceutical Sciences Review, IV, 1-10.
    MHRA : Naseem, Urooj, Ayesha Ayub, and Fatima Iqbal. 2019. "Use of Fluorescent Probe for the Fast and Quantitative Detection of Chemicals in the Blood." Global Pharmaceutical Sciences Review, IV: 1-10
    MLA : Naseem, Urooj, Ayesha Ayub, and Fatima Iqbal. "Use of Fluorescent Probe for the Fast and Quantitative Detection of Chemicals in the Blood." Global Pharmaceutical Sciences Review, IV.I (2019): 1-10 Print.
    OXFORD : Naseem, Urooj, Ayub, Ayesha, and Iqbal, Fatima (2019), "Use of Fluorescent Probe for the Fast and Quantitative Detection of Chemicals in the Blood", Global Pharmaceutical Sciences Review, IV (I), 1-10
    TURABIAN : Naseem, Urooj, Ayesha Ayub, and Fatima Iqbal. "Use of Fluorescent Probe for the Fast and Quantitative Detection of Chemicals in the Blood." Global Pharmaceutical Sciences Review IV, no. I (2019): 1-10. https://doi.org/10.31703/gpsr.2019(IV-I).01

agen228

sbobet88

agen228 login

promo agen228

link alternatif agen228

login pkv games

bola228

bola228

bola228

judi bola

judi bola

liga88

agen228

situs live casino

olb228

olb228

bandarqq

mix parlay

slot gacor

mix parlay

agen bola terpercaya

agen judi bola

casino agen228

https://whitetailsofoklahoma.net/

https://www.usafocs62a.net/

https://www.smithforcps.com/

https://www.prestigeprivateparties.com/

slot gacor

https://bolacepat.com/

https://oswegocountygovernments.com/

link alternatif agen228

mix parlay

https://www.towingpinole.com/

situs slot gacor

agen bola piala dunia 2026

https://esdrasacademy.com/

sbobet88

situs taruhan bola

https://portablegeneratorreview.com/

slot gacor

https://royalhoneyreview.com/

live casino

https://www.atommobile.net/

situs judi bola

agen228

slot gacor hari ini

situs judi bola terpercaya

situs judi bola terpercaya

mix parlay

mix parlay

situs toto

mix parlay

sbobet88

judi bola

Bola62

sbobet

Agen Bola

mix parlay

agen228

sbobet88

judi bola

judi bola

agen228

agen228

agen judi bola

agen sbobet

bandarqq

bola228

slot gacor

parlay

judi bola

judi bola

Bola62

situs bola62

agen228

agen228

bola228

MAHJONG WAYS

bola228

liga88

judi bola

judi bola resmi

sbobet88

nexbola

mix parlay

sbobet88

situs judi bola

bola62

liga62

liga228

bos228

indo365

hokibet228

bolaku

nextbola

winning228

bolaabadi

domino228

liga62

bola62

bola62

bola62

bola62

bola62

liga62

liga62

liga62

liga62

liga228

liga228

indo365

indo365

indo365

asiaqq

asiaqq

asiaqq

bos228

bos228

bos228

bos228

indo365

bola62

liga62

bos228

indo365

https://todossantosmusicfestival.com/kontak/

liga228

https://canapaexpo.com/kontak/

bola62

https://masiacanpalet.com/kontak/

https://alwkil.com/kontak/

https://deepsouthfilm.com/kontak/

https://buylesscrap.org/kontak/

https://realmofcaringfoundation.org/kontak/

https://apostropheuk.com/kontak/

https://atlantajwj.org/kontak/

https://crackstevens.com/kontak/

https://flickoff.org/kontak/

https://doctorzhivagobroadway.com/kontak/

https://lesphillip.com/kontak/

https://puffsofdoom.com/kontak/

https://annieross.net/kontak/

https://shmaltzdeli.com/kontak/

https://fourvee.com/kontak/

https://cardewdesign.com/kontak/

https://cheap-heat.com/kontak/

nextbola

nextbola

nextbola

nextbola

bolaabadi

bolaabadi

bolaabadi

bolaabadi

bolaabadi

domino228

bandarq228

bolaku

winning228

nextbola

bolaabadi

nextbola

bolaku

hokibet228

winning228

bolaabadi

nextbola

bolaku

hokibet228

winning228

nextbola

nextbola

bola62

bola62

bola62

liga62

liga62

liga62

bola62

bola62

liga62

liga62

liga62

bola62

liga62

liga62

mahjong

https://dev.pybcn.org/

sbobet88

parlay

prediksi parlay

https://tridentsdesign.com/portfolio-filter/

https://raleighcraigslist.com/

judibola.it.com

judi bola

liga62

liga62

bola62

liga62

liga62

liga62

liga62

bola62

liga62

liga62

bola62

bola228

bola62

liga228

https://heylink.me/www.bola228.org/

bola228

bola62

rtp gacor hari ini/

Slot Gacor malio805

prediksi judi bola

Situs Slot Gacor Hari Ini

olb228

agen228

agen228

bola62

liga88

JUDI BOLA ONLINE

bola228

liga88

liga88

olb228

olb228

olb228

olb228

agen228

agen228

agen228

imcpoker

poker855

dewaqq

dewaqq

https://var-orthopedie.com/product/chausson-articule-bebax/

https://var-orthopedie.com/product/genouillere-rotulienne-genu-pro-active/

https://var-orthopedie.com/

https://equimondia.com/

https://equimondia.com/nos-produits/largile-blanche-bentonite/

https://equimondia.com/nos-produits/11-6-spiruline-cheval-organique-html/

judi bola

https://sabonelaundry.fr/blog-list/

https://sabonelaundry.fr/sabone-laundry-sabone-laundry-blanchisserie-marseille/

agen228

agen228

agen228

liga88

liga88

agen228

agen228

agen228

judi bola resmi

bola62

bola62

liga88

agen228

agen228

agen228

liga228

liga228

dewaqq

bola62

https://www.singapura.nyc/contact/

judi bola

bermain pola mahjong ways 2

permainan mahjong ways 2

fokus di mahjong wins 3

pola grid mahjong wins 3

Kompleksitas Permainan Mahjong Ways 2

Game Penghasil Saldo DANA Masih Diminati

Sistem RTP Pragmatic Mahjong Scatter Hitam

Strategi Mahjong Wins 3 Berbasis Data

Membaca Pola Grid Mahjong Wins 3

Menjaga Fokus di Mahjong Wins 3

pola rtp live mahjong 3 di ambang kebangkrutan

bangkit setelah menemukan pola rtp live mahjong 3

utang numpuk hingga bangkit berkat mahjong 3

pola mahjong 3 jadi titik pengusaha hamper gulung tikor

strategi rtp live mahjong 3 menghubah segalanya

liga88

mix parlay

agen228

  • agen bola parlay
  • slot gacor online gampang pecah
  • https://www.christianmonitor.org/

    judi bola parlay

    https://www.papajohnspizza.mx/

    https://www.musichelpsheal.org/

    kofbola link

    https://www.kyndrasteinmann.com/

    https://rentaljogja.co.id/

    https://www.profilelinker.com/contact/

    https://www.ayrag.com/

    taruhan bola kofbola

    https://www.stikes-whs.ac.id/