Implants are sterile and small cylinders of active drug utilized for slow absorption and prolong action should be administered below skin, muscle or tissue. Implants are based on the principle that many drugs and hormones are insoluble in aqueous solvents which enables them to provide slower dissolution for required therapeutic effects. Implants should be biocompatible with tissues of the human body. Its surface properties should be compliant depending on surface tension and roughness. Materials treated by multiple techniques for the nanoscale modified surface. These techniques include physical, chemical and mechanical modifications. Materials are selected on the basis of inertness, tolerance and activity in the body. Metals, ceramics, carbon materials and polymers are utilized for this. Carbon nanotubes, graphene, hydroxyapatite, zirconia, titanium alloys, silver, silica and polymers are used as implants. Applications of nanotechnology in implants are discussed.