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ENHANCING BIOAVAILABILITY WITH OROMUCOSAL PRODUCTS OPPORTUNITIES AND CHALLENGES

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04 Pages : 37-48

http://dx.doi.org/10.31703/gpsr.2023(VIII-IV).04      10.31703/gpsr.2023(VIII-IV).04      Published : Dec 2023

Enhancing Bioavailability with Oromucosal Products: Opportunities and Challenges

Abstract

    The oral mucosa offers an attractive route for the systemic delivery of drugs. The bioavailability and effectiveness of many drugs can be increased by administering them through the oral mucosa which bypasses the first-pass metabolism effect. This article will discuss principles, application areas, benefits & drawbacks as well as possible future perspectives for the study and development of oromucosal drug delivery systems. Among the critical benefits of administering drugs via the mouth is that it starts acting fast, is easily absorbed into the bloodstream, makes it easier for patients to follow their prescriptions as well and offers more freedom in terms of dosage control. The article emphasizes innovative technologies such as nanoparticulate formulations as well as microfabricated devices which are slated to improve drug targeting and delivery. It also touches on such related issues as taste masking, variability in bioavailability, and regulatory concerns.

    romucosal Drug Delivery, Bioavailability, Patient Compliance, Drug Targeting, Safety Considerations, Innovative Technologies, Future Directions

    (1) Syed Muhammad Talha
    Graduate Scholar, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Pakeeza Zainab
    Graduate Scholar, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (3) Mamoona Khalid
    Graduate Scholar, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (4) Areej Javed
    Graduate Scholar, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
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Cite this article

APA

    APA : Talha, S. M., Zainab, P., & Khalid, M. (2023). Enhancing Bioavailability with Oromucosal Products: Opportunities and Challenges. Global Pharmaceutical Sciences Review, VIII(IV), 37-48. https://doi.org/10.31703/gpsr.2023(VIII-IV).04

CHICAGO

    CHICAGO : Talha, Syed Muhammad, Pakeeza Zainab, and Mamoona Khalid. 2023. "Enhancing Bioavailability with Oromucosal Products: Opportunities and Challenges." Global Pharmaceutical Sciences Review, VIII (IV): 37-48 doi: 10.31703/gpsr.2023(VIII-IV).04

HARVARD

    HARVARD : TALHA, S. M., ZAINAB, P. & KHALID, M. 2023. Enhancing Bioavailability with Oromucosal Products: Opportunities and Challenges. Global Pharmaceutical Sciences Review, VIII, 37-48.

MHRA

    MHRA : Talha, Syed Muhammad, Pakeeza Zainab, and Mamoona Khalid. 2023. "Enhancing Bioavailability with Oromucosal Products: Opportunities and Challenges." Global Pharmaceutical Sciences Review, VIII: 37-48

MLA

    MLA : Talha, Syed Muhammad, Pakeeza Zainab, and Mamoona Khalid. "Enhancing Bioavailability with Oromucosal Products: Opportunities and Challenges." Global Pharmaceutical Sciences Review, VIII.IV (2023): 37-48 Print.

OXFORD

    OXFORD : Talha, Syed Muhammad, Zainab, Pakeeza, and Khalid, Mamoona (2023), "Enhancing Bioavailability with Oromucosal Products: Opportunities and Challenges", Global Pharmaceutical Sciences Review, VIII (IV), 37-48

TURABIAN

    TURABIAN : Talha, Syed Muhammad, Pakeeza Zainab, and Mamoona Khalid. "Enhancing Bioavailability with Oromucosal Products: Opportunities and Challenges." Global Pharmaceutical Sciences Review VIII, no. IV (2023): 37-48. https://doi.org/10.31703/gpsr.2023(VIII-IV).04