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DETERMINATION OF PERCUTANEOUS ABSORPTION OF POLYPHENOLS FROM NATURAL EXTRACTS BY USING FRANZ CELL

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02 Pages : 18-23

http://dx.doi.org/10.31703/gpsr.2023(VIII-III).02      10.31703/gpsr.2023(VIII-III).02      Published : Sep 2023

Determination of Percutaneous Absorption of Polyphenols from Natural Extracts by using Franz Cell

Abstract

    This investigation aimed to explore the bioactive compound potential in medicinal plants such as polyphenols and to test the total phenol content as well as the velocity of skin absorption and antioxidant activities of crude extracts from plants and fruits. albino rats and the Franz diffusion model was used for experimentation.Raphanus sativus proved to have the most substantial phenolic content following Beta vulgaris and Rosa indicat.Analyzed compounds led to skin permeation as Malus domestica had the highest absorbent value among all tested compounds. In addition to that, all extracts were potent DPPH radical scavengers and out of these Daucus carota oil was presented with the best antioxidant ability. The outcome of these experiments advocates for constant research and the growth of highly efficient transdermal delivery systems and aesthetic concoctions with the inherent healing from nature.

    Antioxidants, Medicinal Plants, Total Phenolic content, Franz cell, DPPH, Transdermal Drug Delivery System (TDDS)

    (1) Asif Ali
    MPhil, Department of Pharmaceutics, The Islamia University of Bahawalpur, Punjab, Pakistan.
    (2) Muhammad Shoaib Khan
    MPhil, Department of Pharmaceutics, The Islamia University of Bahawalpur, Punjab, Pakistan.
    (3) Hafiz Muhammad Usman Abid
    MPhil, Department of Pharmaceutics, The Islamia University of Bahawalpur, Punjab, Pakistan.
    (4) Farhan Mukhtar
    MPhil, Department of Pharmaceutics, The Islamia University of Bahawalpur, Punjab, Pakistan.
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Cite this article

APA

    APA : Ali, A., Khan, M. S., & Abid, H. M. U. (2023). Determination of Percutaneous Absorption of Polyphenols from Natural Extracts by using Franz Cell. Global Pharmaceutical Sciences Review, VIII(III), 18-23. https://doi.org/10.31703/gpsr.2023(VIII-III).02

CHICAGO

    CHICAGO : Ali, Asif, Muhammad Shoaib Khan, and Hafiz Muhammad Usman Abid. 2023. "Determination of Percutaneous Absorption of Polyphenols from Natural Extracts by using Franz Cell." Global Pharmaceutical Sciences Review, VIII (III): 18-23 doi: 10.31703/gpsr.2023(VIII-III).02

HARVARD

    HARVARD : ALI, A., KHAN, M. S. & ABID, H. M. U. 2023. Determination of Percutaneous Absorption of Polyphenols from Natural Extracts by using Franz Cell. Global Pharmaceutical Sciences Review, VIII, 18-23.

MHRA

    MHRA : Ali, Asif, Muhammad Shoaib Khan, and Hafiz Muhammad Usman Abid. 2023. "Determination of Percutaneous Absorption of Polyphenols from Natural Extracts by using Franz Cell." Global Pharmaceutical Sciences Review, VIII: 18-23

MLA

    MLA : Ali, Asif, Muhammad Shoaib Khan, and Hafiz Muhammad Usman Abid. "Determination of Percutaneous Absorption of Polyphenols from Natural Extracts by using Franz Cell." Global Pharmaceutical Sciences Review, VIII.III (2023): 18-23 Print.

OXFORD

    OXFORD : Ali, Asif, Khan, Muhammad Shoaib, and Abid, Hafiz Muhammad Usman (2023), "Determination of Percutaneous Absorption of Polyphenols from Natural Extracts by using Franz Cell", Global Pharmaceutical Sciences Review, VIII (III), 18-23

TURABIAN

    TURABIAN : Ali, Asif, Muhammad Shoaib Khan, and Hafiz Muhammad Usman Abid. "Determination of Percutaneous Absorption of Polyphenols from Natural Extracts by using Franz Cell." Global Pharmaceutical Sciences Review VIII, no. III (2023): 18-23. https://doi.org/10.31703/gpsr.2023(VIII-III).02