http://dx.doi.org/10.31703/gpsr.2023(VIII-I).14
10.31703/gpsr.2023(VIII-I).14
Published : Mar 2023
Frequency of hemoglobinopathies in Children Presenting with Pallor to Pediatrics Clinic HMC/IBP
The aim of this study was to collect data on different haemoglobin disorders in children who presented to the pediatric clinic at HMC/IBP with pallor and microcytic hypochromic anaemia on peripheral smears. This cross-sectional retrospective study was conducted in the HMC Pediatric IBP Clinic over a period of 4 years from 2018 to 2022. The blood samples were collected from patients with anaemia. All the data was analyzed using SPSS. A total of 48 children (21.6%) were diagnosed with various hemoglobinopathies, while 29 cases (13%) were classified as "undetermined" due to being borderline or requiring repeat electrophoresis. Additionally, 35 children (15.8%) were found to have other causes of anaemia. Hemoglobinopathies are a public health issue and more so in a resource-limited country like Palristan. One of the contributing causes of anaemia in the pediatric age group is hemoglobinopathies.
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Beta Thalassemia, Hemoglobinopathies, Sickle Cell Disease, Anemia, Hb Electrophoresis
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(1) Ambreen Ahmad
FCPS/ Associate Professor, Department of Pediatrics, HMC/Khyber Gilds Medical College, Peshawar, KP, Pakistan.
(2) Samina Shams
FCPS/ Assistant Professor, Department of Pediatrics Hayatabad Medical Complex, Peshawar, KP, Pakistan.
(3) Samreen Ahmad
FCPS/ Professor, Department of Pediatrics, Peshawar General Hospital, Peshawar, KP, Pakistan.
- Abolghasemi, H., Amid, A., Zeinali, S., Radfar, M. H., Eshghi, P., Rahiminejad, M. S., Ehsani, M. A., Najmabadi, H., Ahbari, M. T., Afrasiabi, A., Akhavan Niaki, H., &i Hoorfar, H. (2007). Thalassemia in Iran. Journal of Pediatric Hematology Oncology, 29(4), 233-238. https://doi.org/10.1097/mph.Qb013e3180437e02
- Akram, S., Khattak, S. A. K., Khan, M. A., &Khan, M. A. (2021). Prevalence of haemoglobinopathies in diildren presenting with anemia at DHQ hospital Zhob, Balochistan. Journal of Liaquat University of Medical &Health Sciences, 20(5), 314-318. http ://ois.lumhs.edu.ph/index.php/ilumhs/article/view/678
- Bender, M. A., Yusuf, C., Davis, T., Dorley, M. C., Del Pilar Aguinaga, M., Ingram, A., Chan, M. S., Ubaike, J. C., Hassell, K. L., Ojodu, f, fitHulihan, M. M. (2020). Newborn Screening Practices and Alpha-Thalassemia Detection — United States, 2016. Morbidity and Mortality WeeMy Report, 69(36), 1269-1272. https://doi.org/10.15585/mmwirmm6936a7
- Brancaleoni, V., Di Pierro, E., Motta, I., &i Cappellini, M. D. (2016). Laboratory diagnosis of thalassemia. International Journal of Laboi'atoiy Hematology, 38, 32-40. https://doi.org/10.llll/ijlh.12527
- Ghani, R., Manji, M. A., & Ahmed, N. (2002). Hemoglobinopathies among five major ethnic groups in Karachi, Pakistan. PubMed, 33(4), 855-861. https://pubmed.ncbi.nlm.nih.gov/12757239
-
Hafeez, M., Aslam, M., Ali, A., Rashid, Y.,
https://pubmed.ncbi.nlm.nih.gov/17374299 - Hamamy, H., &A1-Allawi, N. (2012). Epidemiological profile of common haemoglobinopathies in Arab countries. Journal of Community Genetics, 4(2), 147-167 . https://doi.org/10.1007/sl2687-012-Q127-8
- Hussain, J., Khan, H. U., Ali, S. A., fit fan, M. A. (2015). Haemoglobanopathies in Southern areas of Klryber Pakhtunkhwa. Journal of Medical Sciences, 23(2), 73-76. https://jinedsci.com/index.php/lmedsci/article/view/221
- Origa, R. (2017). -Thalassemia. Genetics in Medicine, 19(6), 609-619. https://doi.org/10.1038/qim.2016.173
- Shabbir, S., Nadeem, M. A., Sattar, A., Ara, I., Ansari, S. H., Farzana, T., Taj, M., Borhany, M., Manzir, S., Zaidi, U., Hassan, J., Naz, A., & Sham si, T. (2016). Type and frequency of hemoglobinopathies, diagnosed in the area of Karachi, in Pakistan. Cogent Medicine, 3(1), 1188875. https://doi.org/10.1080/2331205x.2Q16.1188875
- Walreed, U., Satti, H., Farooq, N., & Zaheer, H. (2012). Frequency of haemoglobinopathies: a single-centre, cross-sectional study from Islamabad, Pakistan. EMHJ-Eastern Mediterranean Health Journal, 18 (12), 1257- 1259, 2012. https://doi.org/10.26719/2012.18.12.1257
Cite this article
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APA : Ahmad, A., Shams, S., & Ahmad, S. (2023). Frequency of hemoglobinopathies in Children Presenting with Pallor to Pediatrics Clinic HMC/IBP. Global Pharmaceutical Sciences Review, VIII(I), 97-101. https://doi.org/10.31703/gpsr.2023(VIII-I).14
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CHICAGO : Ahmad, Ambreen, Samina Shams, and Samreen Ahmad. 2023. "Frequency of hemoglobinopathies in Children Presenting with Pallor to Pediatrics Clinic HMC/IBP." Global Pharmaceutical Sciences Review, VIII (I): 97-101 doi: 10.31703/gpsr.2023(VIII-I).14
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HARVARD : AHMAD, A., SHAMS, S. & AHMAD, S. 2023. Frequency of hemoglobinopathies in Children Presenting with Pallor to Pediatrics Clinic HMC/IBP. Global Pharmaceutical Sciences Review, VIII, 97-101.
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MHRA : Ahmad, Ambreen, Samina Shams, and Samreen Ahmad. 2023. "Frequency of hemoglobinopathies in Children Presenting with Pallor to Pediatrics Clinic HMC/IBP." Global Pharmaceutical Sciences Review, VIII: 97-101
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MLA : Ahmad, Ambreen, Samina Shams, and Samreen Ahmad. "Frequency of hemoglobinopathies in Children Presenting with Pallor to Pediatrics Clinic HMC/IBP." Global Pharmaceutical Sciences Review, VIII.I (2023): 97-101 Print.
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OXFORD : Ahmad, Ambreen, Shams, Samina, and Ahmad, Samreen (2023), "Frequency of hemoglobinopathies in Children Presenting with Pallor to Pediatrics Clinic HMC/IBP", Global Pharmaceutical Sciences Review, VIII (I), 97-101
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TURABIAN : Ahmad, Ambreen, Samina Shams, and Samreen Ahmad. "Frequency of hemoglobinopathies in Children Presenting with Pallor to Pediatrics Clinic HMC/IBP." Global Pharmaceutical Sciences Review VIII, no. I (2023): 97-101. https://doi.org/10.31703/gpsr.2023(VIII-I).14